BRADENTON, Fla. — A biomedical institute on Florida’s east coast is exploring replacing its planned conduit issuer in hopes of lowering the cost of selling $70 million of bonds to finance the construction of a research ­facility.

The nonprofit Vaccine and Gene Therapy Institute of Florida, a new division of Oregon Health and Science University, had planned to use the Southern Grove Community Development District as the conduit issuer for the transaction — a CDD created for this specific purpose and the first of its kind to be used this way in Florida.

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