CHICAGO — Rochester, Minn.-based Mayo Clinic hopes to land $500 million of state bonding help over the next two decades to support a proposed $5 billion capital improvement and economic development plan that aims to both improve its own facilities and remake its home city.

The initiative dubbed Destination Medical Center is designed to enhance the prestigious clinic’s draw internationally as a health care destination over the long-term. The plan includes Mayo’s previously announced investment of $3.5 billion in its capital facilities on the Rochester campus and other facilities in the coming years. In addition, the plan relies on $2.1 billion in private investment and $585 million in state and local aid to support public infrastructure improvements for the city makeover.

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